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4F-PHP may also go by the name?4-fluro-pyrrolidinohexiophenone. It is an analog of the compound alpha-pyrrolidinohexiophenone with 4F-PHP distinguished from its parent compound by having the aromatic ring fluorinated in the para position. Fluorination of drug compounds can sometimes increase bioavailability and lipophilicity and the highly electronegative character of fluorine can change the topographical charge of the molecule interfering with metabolism and giving the compound a longer half-life. The electronegative fluorine atom should make the carbonyl less polar and reduce the reactivity of the compound. Where to buy 4F-PHP online.
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4F-PHP belongs to the class of chemicals known as substituted cathinone. The substituted cathinone is a series of compounds that feature a phenethylamine backbone with a ketone at the beta carbon and various alkyl moieties substituted at the alpha carbon adjacent to the amine. 4F-PVP and -PHP has a butyl substitute at the alpha carbon. This confers increased lipophilicity to this particular cathinone. The nitrogen itself is transformed into a pyrrolidine moiety as it forms a five-member ring with four other carbons. Many of the cathinone compounds have stimulatory effects when consumed. Some induce states of euphoria and some act as entactogens. They are related to the chemical compound cathinone, a substance derived from the plant Khat which is native to the horn of Africa.
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Khat is an ethnobotanical with a long history of use by indigenous people. The method of administration was to chew on the leaf, releasing the cathinone compound to induce the desired pleasant stimulatory effect. Substituted cathinone, by contrast, has a much shorter period of human usage with the use of compounds like?mephedrone?and methylone first being reported in the last 15 years. These compounds reached widespread popularity due to availability online and reported effects similar to the traditional psychoactive like MDMA, and amphetamine.
Due to increasingly restrictive legislation prohibiting the sale of these compounds new generations of substituted cathinone have emerged including MDPV, ?-PVP, ?-PHP, and 4F-PVP. Changes in structure can have large differences in subjective effects, duration of action, side effects, and toxicity.
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Owing to the wide variety of emerging cathinone there is often a paucity of information regarding the effect profiles of many members of this class of drugs. Continual modifications are made in order to attempt to circumvent legislation.?-PHP, a close relation of 4F-PHP was reported to be an effective stimulant that induced a rush, feelings of alertness, and euphoria. Perhaps owing to the similarity 4F-PHP may have similar effects. Order 4F-PHP Crystals online
4F-PHP is an extremely new compound. As such, there is no research into the pharmacological and toxicological profile of this compound and its potentially deleterious effects when used in humans. 4f-PHP crystals are not for consumption by animals or humans. Subjective and unverifiable online reports suggest this compound is reasonably potent and induces euphoria, rush, and stimulation.